The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
نویسنده
چکیده
PURPOSE The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating recurrent pterygia. METHODOLOGY An interventional, prospective, comparative clinical study was performed in 30 eyes (26 patients) with recurrent pterygia, allocated into two groups: Group A (19 eyes) operated by pterygium excision and limbal-conjunctival autograft transplantation (L-CAT) without MMC and Group B (20 eyes) operated with injection of 0.1 mL of MMC 0.15 mg/mL 1 month before L-CAT surgery. Exclusion criteria included patients with symblepharon, cicatricial conjunctival diseases, limbal stem cell deficiency, and other intraocular diseases. RESULTS A total of four cases of recurrences for Group A (P = 0.012) and one case of recurrence for Group B (P < 0.001) were recorded. CONCLUSIONS Preoperative injection of MMC in low dose and concentration improves the results of L-CAT in recurrent pterygium.
منابع مشابه
Treatment of pterygium: Comparison of four transplantation methods
Introduction: Pterygium, one of the degenerative and prevalent ophthalmic diseases, is more prevalent in equatorial and tropical areas. This study was conducted in order to compare recurrence rate and surgical complications of pterygium treatment with four different transplantation methods of conjunctival autograft, conjunctival flap, using mitomycin-C with conjunctival autograft and using mi...
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PURPOSE To report the incidence of recurrence after primary pterygium surgery using either a free conjunctival or limbal-conjunctival autograft without antimetabolites. METHODS One hundred eleven eyes of 90 patients underwent pterygium resection; a free conjunctival autograft was used in 88 surgeries and a free limbal-conjunctival autograft in 24; the latter technique was reserved for dark-sk...
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BACKGROUND Treatment of recurrent pterygium associated with symblepharon usually involves the use of tissue grafting and/or the intraoperative application of mitomycin C (MMC). For the graft, a conjunctival/limbal autograft and/or amniotic membrane may be used. This generally requires extra technical skills and assistance, an increase in the cost and duration of surgery, and a more extensive an...
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